The federal Ready, Set, PrEP program ended July 2025. Many websites still list it as active. See what replaced it →

Free PrEP in St. Louis

Missouri is a statewide EHE priority jurisdiction — one of only 7 states designated for substantial rural HIV burden. St. Louis anchors the state's HIV infrastructure, but the legislative environment is among the nation's most hostile: 67 anti-trans bills tracked in 2025, gender-affirming care banned at all ages via Medicaid. Thirteen Missouri counties rank in the CDC's top 5% most vulnerable to HIV outbreaks. EHE funding has established 3 new PrEP clinics in previously unserved rural southeast Missouri.

No State PrEP DAP Medicaid Expanded EHE Priority (Statewide)

HIV at a Glance

~600 new diagnoses/yr · 13 counties in CDC top 5% vulnerability · EHE statewide

Fastest Path to Free PrEP in St. Louis

1

Start with MISTR (fastest)

Free telehealth PrEP — consultations, at-home labs, medication delivery, all at $0. Works whether you have insurance or not. No ID required.

2

If you have insurance

PrEP is legally free under the ACA (upheld June 2025). Your insurer must cover medication, labs, and visits at $0. If charged, file a complaint with your state insurance commissioner.

3

Check MO HealthNet

PrEP covered at $0 via MO HealthNet. Enroll: mydss.mo.gov or 855-373-4636.

4

If uninsured: Gilead Advancing Access

Free medication for uninsured at ≤500% FPL. No immigration requirement. Covers Truvada, Descovy, and Yeztugo. Call 1-800-226-2056. Pair with an FQHC for free labs.

Get PrEP delivered free in St. Louis

MISTR provides free telehealth PrEP in Missouri — consultations, at-home labs, medication, and delivery at $0.

ANDR735

Use code ANDR735 when you sign up — it helps keep FreePrEP.org running so others can find free PrEP too.

Missouri Programs & Assistance

Missouri expanded Medicaid in 2021. MO HealthNet covers PrEP at $0 as a preventive service. However, Missouri's anti-LGBTQ+ legislative environment creates a chilling effect on accessing sexual health services.

Clinics & Community Resources

Full-Service PrEP

Planned Parenthood Great Rivers

St. Louis

PrEP at all locations and via telehealth for MO and IL residents.

📞 (314) 531-7526

ppslr.org/telehealth

HIV Services

Vivent Health St. Louis

St. Louis

PrEP, testing, case management, pharmacy. Formerly AIDS Foundation.

viventhealth.org

HIV Services

Vivent Health Kansas City

Kansas City

Serves KC metro including Kansas residents.

viventhealth.org/kansascity

Regional HIV Services

AIDS Project of the Ozarks

1636 S. Glenstone Ave, Suite 100, Springfield

Walk-in testing Mon-Thu. PrEP for uninsured on sliding scale. Covers 29 SW Missouri counties.

📞 (417) 881-1900

apo-ozarks.org

Related Guides

Free PrEP in Kansas City → Free PrEP in Chicago → Free PrEP Online → Full Missouri PrEP Guide →

Information sourced from HIV.gov, CDC, NASTAD, AIDSVu, and state health departments. FreePrEP.org is an independent resource — not affiliated with any government agency or pharmaceutical company. Full disclosure