What was Ready, Set, PrEP?
Launched in December 2019 as part of the HHS "Ending the HIV Epidemic" initiative, Ready, Set, PrEP was the only federal program providing free PrEP medication to uninsured individuals with a valid prescription. Administered by TrialCard at getyourprep.com, it covered the cost of the medication itself — though not lab work or clinical visits.
The program stopped accepting new enrollments on July 30, 2024 and fully shut down on July 18, 2025.
Many websites still reference this program as active
As of March 2026, pages on Planned Parenthood, state health departments, Greater Than HIV, and dozens of community organizations still direct people to Ready, Set, PrEP. If you've been sent to getyourprep.com and found it no longer working — this is why.
What replaced it?
Nothing. No new federal program has been established to fill this gap. This is the single most significant change in the US PrEP access landscape in years.
However, several alternatives exist that can provide free or nearly free PrEP. Here's what actually works right now:
Telehealth platforms with 340B partnerships
Platforms like MISTR cover everything — medication, labs, and consultations — at $0 for both insured and uninsured patients in all 50 states. They partner with 340B-eligible health centers and navigate manufacturer assistance programs on your behalf. This is the closest thing to a Ready, Set, PrEP replacement that exists.
Using this code helps keep FreePrEP.org running and connects more people with free PrEP.
Start free with MISTRAffiliate referral — we may earn a small fee at no cost to you. Disclosure
Gilead Advancing Access — Medication Assistance Program
Free brand-name Descovy or Yeztugo for uninsured patients with income under 500% FPL (~$75,300/year). No SSN required. Ships via FedEx overnight. This covers the medication, but you'll need a separate source for labs and clinical visits.
Apply at prep.advancingaccess.comOr call 1-800-226-2056
Federally Qualified Health Centers
Nearly 1,400 FQHCs across ~15,000 sites provide healthcare on a sliding fee scale. Many prescribe PrEP and provide the required lab work. You can never be turned away for inability to pay.
Find a health center near youState PrEP Drug Assistance Programs
If you live in California, Colorado, DC, Illinois, Indiana, Iowa, Massachusetts, New Mexico, New York, Oklahoma, Virginia, or Washington — your state runs its own PrEP assistance program. The remaining 38+ states have no equivalent.
Check your stateKey difference: Ready, Set, PrEP only covered medication
It's worth noting that Ready, Set, PrEP only covered the cost of the PrEP pills — not the required lab work (HIV test, kidney function, STI screening) or clinical visits needed to get and maintain a prescription. Many people who used the program still faced out-of-pocket costs for these services.
Ironically, the telehealth alternatives available today often provide more comprehensive coverage than Ready, Set, PrEP did — MISTR, for example, covers medication, at-home lab kits, and clinical consultations all at $0.
What about generic PrEP?
Here's the catch: Gilead MAP only provides brand-name Descovy and Yeztugo — not generic TDF/FTC. And Gilead stopped providing free generic Truvada in January 2025. If you specifically need generic PrEP and have no insurance, your options are limited to state PrEP DAPs (12 states), FQHCs, or paying out of pocket with a GoodRx coupon (~$30–$50/month).
Our recommendation
If you were using Ready, Set, PrEP and need a new path: start with the eligibility tool. It'll match you with every program you qualify for based on your insurance status, state, and income. Takes 60 seconds.