Medicare PrEP Coverage: The Basics

In September 2024, CMS finalized a National Coverage Determination that adds PrEP to Medicare Part B's preventive services. This means:

Before this change: PrEP was covered under Medicare Part D (prescription drug plans), which meant copays, deductibles, and the coverage gap. The Part B coverage path now offers a completely free option.

Part B vs. Part D for PrEP

FeaturePart B (new)Part D
Cost to you$0Varies (up to $2,100 annual OOP cap)
DeductibleNone for preventivePlan-specific
Covers labs/visitsYes, at $0Separate Part B billing
Prior authorizationMay be requiredMay be required
Best forLowest possible costBackup if Part B claim denied

Your provider should bill PrEP under Part B for the best coverage. If there's an issue, Part D remains a backup option with the $2,100 annual OOP cap.

Medicare or not, PrEP is free

MISTR works with Medicare and all insurance types. Free consultation, free labs, free medication, free delivery.

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HIV in Older Adults: Why PrEP Matters After 50

People over 50 accounted for approximately 17% of new HIV diagnoses in recent CDC data. Factors that increase risk in this age group include:

PrEP is approved for adults of all ages. If you're sexually active and at any risk of HIV exposure, age is not a reason to avoid PrEP.

How to Start PrEP on Medicare

PrEP from the comfort of home

MISTR offers telehealth consultations — no waiting room, no commute. Free for Medicare patients.

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Using this code at signup helps us achieve our mission of getting free PrEP out to all who need it.

Frequently Asked Questions

Does Medicare Advantage cover PrEP?
Yes. Medicare Advantage plans must provide all benefits covered under Original Medicare, including Part B PrEP coverage at $0.
I'm on Medicaid and Medicare (dual eligible). How does PrEP work?
As a dual-eligible beneficiary, PrEP should be covered at $0 through either Medicare Part B or Medicaid. Your provider can bill whichever offers the simplest path.
Will my Medicare provider prescribe PrEP?
Any licensed provider can prescribe PrEP. If yours is unfamiliar or reluctant, a telehealth service like MISTR can prescribe and manage your PrEP independently.
Is PrEP safe for older adults?
Yes. PrEP is well-studied in adults of all ages. Your provider will monitor kidney function quarterly, which is especially important as kidney function naturally declines with age. Descovy has a slightly better kidney and bone safety profile than Truvada.