Fastest Path to Free PrEP
PrEP is covered at $0 under ACA. Use the Gilead Co-Pay Coupon (1-877-505-6986) for any remaining costs.
SC Medicaid covers only children, pregnant women, elderly, disabled, very low-income parents. 105,000-340,000+ residents in coverage gap.
Compare online and local PrEP access options before choosing a provider. Or Q Care Plus via PALSS — 99% of patients pay $0.
SC Department of Public Health PrEP initiative. Email: PrEPMeSC@dph.sc.gov. AIDS Hotline: 1-800-322-AIDS.
State Programs & Assistance
No State PrEP DAP
South Carolina has no PrEP DAP. SC DAP is for HIV-positive individuals only. Pharmacists cannot prescribe PrEP.
SC Medicaid (NOT Expanded)
Coverage gap affects 105,000-340,000+ residents, with 38% of Black South Carolinians at risk.
Phone: 1-888-549-0820
PrEPMeSC Initiative
Statewide PrEP awareness campaign by SC Department of Public Health. SC is one of 7 EHE rural priority states.
Clinics & Community Resources
MUSC Infectious Disease Clinic
Academic Medical Center
135 Rutledge Ave, 7th Floor, Charleston
(843) 792-4541
PrEP through infectious disease department.
Palmetto Community Care
ASO
6296 Rivers Ave, Suite 310, N. Charleston
(843) 747-2273
PrEP navigation, testing, community support.
CAN Community Health
Community Health
Columbia, SC
(800) 939-2022
PrEP services across South Carolina.
AID Upstate
ASO
811 Pendleton St, Greenville
(864) 250-0607
PrEP access for Upstate South Carolina.
HopeHealth Inc.
FQHC Network
Aiken, Florence, Orangeburg
(803) 643-1977
Rural PrEP access. Florence: (843) 667-9414. Orangeburg: (803) 535-2272.
Telehealth PrEP Options
Q Care Plus + PALSS
Free (99%)
Partners with PALSS in SC. 99% of patients pay $0. Covers undocumented and uninsured.
Learn more →True U Clinic
$179/consult
Virtual PrEP + gender-affirming HRT (estrogen only in SC).
HIV & PrEP Data
55% of new diagnoses among African Americans (26.3% of population). 86% attributed to MSM exposure. African American incidence: 29.7/100,000 vs White: 5.6/100,000. ~16% of South Carolinians with HIV are unaware of their status.
Know Your Rights
Minor Consent
SC allows minors of any age to consent to STI testing and treatment. PrEP-specific consent is less clear.
HIV Criminalization
SC has HIV-specific criminal laws — felony charges for sexual activity without disclosure.
Gender-Affirming Care
HB 4624 (May 2024) bans gender-affirming care for minors.
Undocumented Residents
MISTR requires no documentation. Q Care Plus + PALSS explicitly covers undocumented and uninsured patients. Gilead PAP has no immigration requirement.