Free PrEP in Wyoming
Wyoming has the most limited PrEP infrastructure of any state: no Medicaid expansion (~9,000 in the coverage gap), no PrEP DAP, no pharmacist prescribing, no Planned Parenthood, no AHF clinics, and the lowest PrEP use rate nationally. Telehealth through a telehealth PrEP provider and Freddie is the primary — often only — pathway to free PrEP.
Fastest Path to Free PrEP in Wyoming
Start with MISTR
For most Wyomingites, MISTR is the fastest and often only path to free PrEP. Completely free — delivered to your door anywhere in the state.
Apply for Gilead Advancing Access
Free Truvada/Descovy if uninsured at ≤500% FPL. Call 1-800-226-2056. No immigration requirement.
Contact WY PrEP Matters
Wyoming DOH contracts with Colorado Health Network for PrEP navigation. Visit wyprepmatters.com or call 1-800-438-1282.
If you have insurance
PrEP is covered at $0 under the ACA. Use the Gilead Co-Pay Coupon for any remaining costs.
Compare PrEP access options
Telehealth providers, local clinics, state programs, Medicaid, and manufacturer assistance can all be valid routes. Compare cost, lab method, medication options, location, privacy, and follow-up instead of defaulting to one provider.
Compare providers and programs →Wyoming PrEP Programs & Assistance
WY PrEP Matters / Colorado Health Network
Wyoming DOH contracts with CHN for PrEP navigation since Wyoming has no in-state infrastructure. Self-referral available.
Gilead Advancing Access
Free Truvada/Descovy for uninsured at ≤500% FPL. The primary free medication pathway in Wyoming.
Clinics & Community Resources
Cheyenne Public Health
HIV/STI services.
📍 100 Central Ave, Cheyenne 82007
One Health
Rural FQHC network in northern Wyoming.
📍 Sheridan, Powell, Greybull, Lovell
Telehealth PrEP Options
Online PrEP provider options
Compare telehealth services, local clinics, public programs, and assistance routes for your state or situation.
Compare providers →Freddie
PrEP for men and transmasculine individuals. Available in all 50 states.
$0 for 90%+ of patients
gofreddie.comHIV & PrEP Data in Wyoming
Wyoming had 22 new diagnoses in 2023 (up from 13 in 2022). An estimated 300-400 people live with HIV — about 50% diagnosed at later stages, indicating massive missed testing opportunities. Wyoming has the lowest PrEP use rate nationally at 3.7 per 100,000. The least populous state (~577,000) with ~5.8 people per square mile — the entire state functions as a provider desert.
Know Your Rights
No Medicaid Expansion
Wyoming is one of only ~10 non-expansion states. ~9,000 residents fall in the coverage gap: too poor for ACA subsidies, not qualifying for Medicaid. Childless adults are categorically ineligible.
No HIV Criminal Laws
Wyoming does not have HIV-specific criminal statutes.
Wind River Reservation
Eastern Shoshone and Northern Arapaho (~27,000 residents). IHS provides healthcare but PrEP access is limited.
Anti-LGBTQ+ Legislation
7 anti-LGBTQ+ bills passed in 2025 including youth GAC ban and religious exemption law (HB 0207).