Free PrEP in Wyoming
Wyoming has the most limited PrEP infrastructure of any state: no Medicaid expansion (~9,000 in the coverage gap), no PrEP DAP, no pharmacist prescribing, no Planned Parenthood, no AHF clinics, and the lowest PrEP use rate nationally. Telehealth through a telehealth PrEP provider and Freddie is the primary — often only — pathway to free PrEP.
Fastest Path to Free PrEP in Wyoming
Start with MISTR
For most Wyomingites, MISTR is the fastest and often only path to free PrEP. Completely free — delivered to your door anywhere in the state.
Apply for Gilead Advancing Access
Free Truvada/Descovy if uninsured at ≤500% FPL. Call 1-800-226-2056. No immigration requirement.
Contact WY PrEP Matters
Wyoming DOH contracts with Colorado Health Network for PrEP navigation. Visit wyprepmatters.com or call 1-800-438-1282.
If you have insurance
PrEP is covered at $0 under the ACA. Use the Gilead Co-Pay Coupon for any remaining costs.
Wyoming PrEP Programs & Assistance
WY PrEP Matters / Colorado Health Network
Wyoming DOH contracts with CHN for PrEP navigation since Wyoming has no in-state infrastructure. Self-referral available.
Gilead Advancing Access
Free Truvada/Descovy for uninsured at ≤500% FPL. The primary free medication pathway in Wyoming.
Clinics & Community Resources
Cheyenne Public Health
HIV/STI services.
📍 100 Central Ave, Cheyenne 82007
One Health
Rural FQHC network in northern Wyoming.
📍 Sheridan, Powell, Greybull, Lovell
Telehealth PrEP Options
Online PrEP provider options
Compare telehealth services, local clinics, public programs, and assistance routes for your state or situation.
Compare providers →Freddie
PrEP for men and transmasculine individuals. Available in all 50 states.
$0 for 90%+ of patients
gofreddie.comHIV & PrEP Data in Wyoming
Wyoming had 22 new diagnoses in 2023 (up from 13 in 2022). An estimated 300-400 people live with HIV — about 50% diagnosed at later stages, indicating massive missed testing opportunities. Wyoming has the lowest PrEP use rate nationally at 3.7 per 100,000. The least populous state (~577,000) with ~5.8 people per square mile — the entire state functions as a provider desert.
Know Your Rights
No Medicaid Expansion
Wyoming is one of only ~10 non-expansion states. ~9,000 residents fall in the coverage gap: too poor for ACA subsidies, not qualifying for Medicaid. Childless adults are categorically ineligible.
No HIV Criminal Laws
Wyoming does not have HIV-specific criminal statutes.
Wind River Reservation
Eastern Shoshone and Northern Arapaho (~27,000 residents). IHS provides healthcare but PrEP access is limited.
Anti-LGBTQ+ Legislation
7 anti-LGBTQ+ bills passed in 2025 including youth GAC ban and religious exemption law (HB 0207).