Free PrEP in Wyoming
Wyoming has the most limited PrEP infrastructure of any state: no Medicaid expansion (~9,000 in the coverage gap), no PrEP DAP, no pharmacist prescribing, no Planned Parenthood, no AHF clinics, and the lowest PrEP use rate nationally. Telehealth through MISTR and Freddie is the primary — often only — pathway to free PrEP.
Fastest Path to Free PrEP in Wyoming
Start with MISTR
For most Wyomingites, MISTR is the fastest and often only path to free PrEP. Completely free — delivered to your door anywhere in the state.
Apply for Gilead Advancing Access
Free Truvada/Descovy if uninsured at ≤500% FPL. Call 1-800-226-2056. No immigration requirement.
Contact WY PrEP Matters
Wyoming DOH contracts with Colorado Health Network for PrEP navigation. Visit wyprepmatters.com or call 1-800-438-1282.
If you have insurance
PrEP is covered at $0 under the ACA. Use the Gilead Co-Pay Coupon for any remaining costs.
Get PrEP delivered free with MISTR
MISTR provides free telehealth PrEP in Wyoming — consultations, at-home labs, medication, and delivery at $0. For most Wyomingites, this is the only realistic free PrEP option.
ANDR735
Use code ANDR735 when you sign up — it helps keep FreePrEP.org running so others can find free PrEP too.
Wyoming PrEP Programs & Assistance
WY PrEP Matters / Colorado Health Network
Wyoming DOH contracts with CHN for PrEP navigation since Wyoming has no in-state infrastructure. Self-referral available.
Gilead Advancing Access
Free Truvada/Descovy for uninsured at ≤500% FPL. The primary free medication pathway in Wyoming.
Clinics & Community Resources
Cheyenne Public Health
HIV/STI services.
📍 100 Central Ave, Cheyenne 82007
One Health
Rural FQHC network in northern Wyoming.
📍 Sheridan, Powell, Greybull, Lovell
Telehealth PrEP Options
MISTR
Free PrEP for all of Wyoming. The most accessible option in the state.
Free — $0 for everything
ANDR735
Freddie
PrEP for men and transmasculine individuals. Available in all 50 states.
$0 for 90%+ of patients
gofreddie.comHIV & PrEP Data in Wyoming
Wyoming had 22 new diagnoses in 2023 (up from 13 in 2022). An estimated 300-400 people live with HIV — about 50% diagnosed at later stages, indicating massive missed testing opportunities. Wyoming has the lowest PrEP use rate nationally at 3.7 per 100,000. The least populous state (~577,000) with ~5.8 people per square mile — the entire state functions as a provider desert.
Know Your Rights
No Medicaid Expansion
Wyoming is one of only ~10 non-expansion states. ~9,000 residents fall in the coverage gap: too poor for ACA subsidies, not qualifying for Medicaid. Childless adults are categorically ineligible.
No HIV Criminal Laws
Wyoming does not have HIV-specific criminal statutes.
Wind River Reservation
Eastern Shoshone and Northern Arapaho (~27,000 residents). IHS provides healthcare but PrEP access is limited.
Anti-LGBTQ+ Legislation
7 anti-LGBTQ+ bills passed in 2025 including youth GAC ban and religious exemption law (HB 0207).