How to Get PrEP for Free in San Juan, Puerto Rico in 2026
San Juan Municipio is an Ending the HIV Epidemic priority jurisdiction — and PrEP access in Puerto Rico has historically been limited, with only a handful of providers on the island. But that's changing. MISTR telehealth now delivers free PrEP across all of Puerto Rico, PRCONCRA pioneered PrEP programs on the island, and Mi Salud (Puerto Rico's Medicaid) covers PrEP as a preventive service. Here's every pathway to $0 PrEP in San Juan and across Puerto Rico.
TL;DR
Free PrEP in San Juan: MISTR telehealth (free in all 50 states, DC, and Puerto Rico — delivered to your door); PRCONCRA (Puerto Rico's pioneer HIV prevention organization, PrEP services, free HIV testing); Mi Salud (PR Medicaid, covers PrEP as preventive service); and Gilead Advancing Access (free medication for uninsured, ≤500% FPL). The CLETS clinic at PRDoH is San Juan's main public HIV/STI services clinic.
Puerto Rico's HIV landscape
San Juan Municipio is Puerto Rico's EHE priority jurisdiction. Puerto Rico has historically faced challenges with PrEP access — a 2019 federal assessment noted only two providers offering PrEP services on the island. Since then, infrastructure has improved through organizations like PRCONCRA and COAI Inc., but access gaps persist, particularly outside the San Juan metro area. MISTR's expansion to Puerto Rico has been a significant development, providing free telehealth PrEP to any address on the island.
Pathways to free PrEP in San Juan
PrEP is covered as a preventive service under federal guidelines. Use the Gilead Co-Pay Coupon (1-877-505-6986) for any remaining medication costs.
Mi Salud covers PrEP as a preventive service. Contact your managed care plan for PrEP provider referrals.
Use MISTR for free telehealth PrEP delivered anywhere in Puerto Rico. Apply for Gilead Advancing Access for free Descovy or Yeztugo (≤500% FPL, call 1-800-226-2056). Visit PRCONCRA for free HIV testing and PrEP services.
MISTR operates in all 50 states, DC, and Puerto Rico. Free consultation, at-home labs, and medication delivered to any PR address. This is often the fastest and most private option on the island.
Get free PrEP delivered anywhere in San Juan
MISTR operates across all of Puerto Rico — PrEP delivered to your San Juan address with no clinic visit required. Free consultation, free labs (at-home or local), and discreet home delivery.
Start free consultation →Using this code at signup helps us achieve our mission of getting free PrEP out to all who need it. MISTR's $0 PrEP is funded through insurance reimbursement and 340B program partnerships — you pay nothing whether you have insurance or not.
San Juan-area providers to know
PRCONCRA (Puerto Rico Community Network for Clinical Research & Health Advancement)
Puerto Rico's pioneer PrEP organization, founded in 1990. Free HIV/STI testing (rapid and conventional), PrEP services, peer education, case management, mental and oral health services. The only organization in Puerto Rico with a specialized prevention and treatment center for youth with or at high risk of HIV. Serves 900+ patients annually. Bilingual services.
CLETS Clinic — PRDoH (Departamento de Salud)
The Puerto Rico Department of Health's main clinic for HIV and STI services in San Juan. PrEP referrals, HIV testing, STI treatment, and linkage to care. Part of PRDoH's OCASET division which administers Ryan White Part B services.
COAI Inc.
Community organization serving LGBTQ+ individuals with HIV prevention workshops, educational activities, PrEP navigation, and community outreach. Extends services beyond the San Juan metro to rural areas of Puerto Rico.
Profamilias
Sexual and reproductive healthcare, gynecology, prenatal services, chronic disease treatment, and vaccinations. PrEP referrals and sexual health counseling.
Migrant Health
Community health services with HIV prevention outreach extending to underserved localities outside the San Juan metro area.
Skip the clinic wait — get PrEP delivered in San Juan
MISTR ships free PrEP to San Juan addresses in 3–5 days. Great option if you want privacy or can't fit a clinic visit into your schedule.
Get started with MISTR →Using this code at signup helps us achieve our mission of getting free PrEP out to all who need it.
Ryan White & ADAP in Puerto Rico
Puerto Rico's Ryan White Part B program, housed under PRDoH's OCASET division, provides care and support services including clinical care, mental health, case management, and medication assistance through ADAP for people living with HIV who are uninsured or underinsured. ADAP covers antiretroviral medications and related costs. For PrEP specifically (for HIV-negative individuals), Gilead Advancing Access and MISTR are the primary free pathways.
ADAP contact: Departamento de Salud, OCASET, Programa Ryan White Parte B · P.O Box 70184, San Juan, PR 00936-8184
Special populations in Puerto Rico
Youth access: PRCONCRA is the only organization in Puerto Rico with a specialized youth HIV prevention center. They serve young people at high risk of HIV with tailored PrEP services, peer education, and psychosocial support.
Rural communities: PrEP access outside San Juan is limited. MISTR telehealth is especially important for rural Puerto Rico — free PrEP delivered to any address on the island eliminates the need to travel to San Juan for a provider.
LGBTQ+ community: COAI Inc. provides community spaces, workshops, and HIV prevention outreach specifically for LGBTQ+ individuals, including in areas outside the metro.
Spanish-speaking: PRCONCRA and local providers operate primarily in Spanish. MISTR's platform is available in English — see our guía en español for Spanish-language guidance.
Not sure which Puerto Rico option is right for you?
A free MISTR consultation can help you decide. If telehealth works, MISTR handles everything. If you need in-person care, they can direct you to the right Puerto Rico provider.
Get started with MISTR →Using this code at signup helps us achieve our mission of getting free PrEP out to all who need it.
Preguntas frecuentes / Frequently asked questions
Can I get free PrEP in Puerto Rico?
Yes. MISTR provides free telehealth PrEP delivered to any address in Puerto Rico — consultation, labs, and medication at $0. PRCONCRA provides free HIV testing and PrEP services in San Juan. Gilead Advancing Access provides free medication for uninsured residents under 500% FPL. Mi Salud (PR Medicaid) covers PrEP as a preventive service.
Does MISTR work in Puerto Rico?
Yes. MISTR explicitly operates in all 50 states, DC, and Puerto Rico. They deliver free PrEP to any Puerto Rico address with no clinic visit required.
How many PrEP providers are there in Puerto Rico?
PrEP provider availability in Puerto Rico has historically been very limited. PRCONCRA is the island's pioneer PrEP provider. MISTR telehealth has significantly expanded access by eliminating the need for an in-person PrEP provider. Contact PRCONCRA at (787) 753-9443 for local referrals.
Does Mi Salud cover PrEP?
Yes. Mi Salud (Puerto Rico's Medicaid managed care) covers PrEP as a preventive service. Contact your managed care plan for PrEP provider referrals and coverage details.
Related guides
Information sourced from state and county health departments, CDC, NASTAD, AIDSVu, and verified provider websites. Last updated April 22, 2026.
FreePrEP.org is an independent public health resource. We maintain editorial independence from our affiliate partners. Information on this page is for educational purposes and is not medical advice. Always consult a licensed healthcare provider about PrEP.